Laura A Dada Selected Research

Adenosine Triphosphatases (ATPase)

12/2021	Maturation of the Na,K-ATPase in the Endoplasmic Reticulum in Health and Disease.
1/2021	TRAF2 Is a Novel Ubiquitin E3 Ligase for the Na,K-ATPase β-Subunit That Drives Alveolar Epithelial Dysfunction in Hypercapnia.
2/2020	Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the β-Subunit of the Enzyme in Alveolar Epithelial Cells.
11/2017	HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.
12/2015	High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation.
1/2012	Evolutionary conserved role of c-Jun-N-terminal kinase in CO2-induced epithelial dysfunction.
9/2011	Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation.
9/2010	Extracellular signal-regulated kinase (ERK) participates in the hypercapnia-induced Na,K-ATPase downregulation.
4/2010	Insulin regulates alveolar epithelial function by inducing Na+/K+-ATPase translocation to the plasma membrane in a process mediated by the action of Akt.
2/2010	Role of ubiquitination in Na,K-ATPase regulation during lung injury.

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Laura A Dada Research Topics

Disease

12	Hypoxia (Hypoxemia) 11/2017 - 04/2003
7	Hypercapnia 01/2021 - 02/2008
6	Lung Injury 01/2018 - 04/2003
5	Edema (Dropsy) 02/2020 - 04/2003
3	Infections 01/2020 - 01/2017
3	Acute Lung Injury 01/2018 - 12/2014
2	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 04/2003
2	Inflammation (Inflammations) 01/2020 - 12/2015
2	Human Influenza (Influenza) 01/2020 - 01/2019
2	Neoplasms (Cancer) 01/2016 - 09/2014
2	Pulmonary Edema 01/2009 - 04/2003
1	Polyploidy 01/2022
1	Hypertrophy 01/2022
1	Nervous System Diseases (Neurological Disorders) 12/2021
1	Pneumonia (Pneumonitis) 01/2019
1	Lung Neoplasms (Lung Cancer) 10/2017
1	Cardiotoxicity 10/2016
1	Heart Failure 10/2016
1	Breast Neoplasms (Breast Cancer) 05/2016
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2015
1	Lung Diseases (Lung Disease) 04/2015
1	Atrophy 04/2015
1	Adenocarcinoma of Lung 09/2014
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2012
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2009

Drug/Important Bio-Agent (IBA)

19	Adenosine Triphosphatases (ATPase)IBA 12/2021 - 04/2003
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2003
7	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2011 - 04/2003
6	UbiquitinIBA 01/2021 - 05/2006
5	AMP-Activated Protein KinasesIBA 12/2015 - 07/2009
3	protein kinase C zetaIBA 11/2017 - 07/2009
3	Small Interfering RNA (siRNA)IBA 09/2010 - 05/2006
2	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021 - 01/2019
2	Adenosine Triphosphate (ATP)IBA 02/2020 - 09/2011
2	CytokinesIBA 01/2019 - 01/2017
2	Protein Isoforms (Isoforms)IBA 01/2018 - 07/2009
2	Messenger RNA (mRNA)IBA 09/2014 - 12/2009
2	Phosphotransferases (Kinase)IBA 09/2011 - 12/2009
2	CatalaseIBA 07/2009 - 05/2006
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 02/2008 - 04/2003
2	Mitochondrial DNA (mtDNA)IBA 05/2006 - 04/2003
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	TNF Receptor-Associated Factor 2 (TRAF2)IBA 01/2021
1	Cell Adhesion MoleculesIBA 02/2020
1	EnzymesIBA 02/2020
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 02/2020
1	Membrane Transport Proteins (Biological Pump)IBA 02/2020
1	sharpinIBA 01/2020
1	tocilizumab (atlizumab)FDA Link 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018
1	Fibronectins (Fibronectin)IBA 10/2017
1	ChemokinesIBA 01/2017
1	Digoxin (Digitek)FDA LinkGeneric 10/2016
1	Cardiac GlycosidesIBA 10/2016
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 05/2016
1	Alanine (L-Alanine)FDA Link 12/2015
1	JNK Mitogen-Activated Protein KinasesIBA 12/2015
1	CateninsIBA 12/2015
1	PaxillinIBA 12/2015
1	Biological ProductsIBA 04/2015
1	Ligases (Synthetase)IBA 09/2014
1	Protein Kinase CIBA 01/2012
1	CalciumIBA 09/2011
1	Calcium Release Activated Calcium ChannelsIBA 09/2011
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 09/2010
1	U 0126 (UO 126)IBA 09/2010
1	cobaltous chloride (cobalt(II)chloride)IBA 12/2009
1	VimentinIBA 12/2009
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 12/2009
1	4- (5- benzo(1,3)dioxol- 5- yl- 4- pyridin- 2- yl- 1H- imidazol- 2- yl)benzamideIBA 12/2009
1	EUK-134IBA 12/2009
1	Hypoxia-Inducible Factor 1IBA 12/2009
1	Cadherins (E-Cadherin)IBA 12/2009
1	Transforming Growth Factors (Transforming Growth Factor)IBA 12/2009
1	Protein Kinases (Protein Kinase)IBA 07/2009
1	Endothelin-1 (Endothelin 1)IBA 01/2009
1	Adrenergic beta-Agonists (beta-Adrenergic Agonists)IBA 02/2008
1	Arginine (L-Arginine)FDA Link 09/2007
1	Monomeric GTP-Binding ProteinsIBA 07/2007
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2007
1	SodiumIBA 01/2007
1	Epithelial Sodium ChannelsIBA 01/2007
1	Glutathione PeroxidaseIBA 05/2006
1	Rieske iron-sulfur proteinIBA 05/2006
1	Proteasome InhibitorsIBA 05/2006
1	Superoxide DismutaseIBA 05/2006
1	Dopamine (Intropin)FDA LinkGeneric 04/2003
1	AntioxidantsIBA 04/2003
1	Peptides (Polypeptides)IBA 04/2003
1	CatecholaminesIBA 04/2003

Therapy/Procedure

1	Critical Care (Surgical Intensive Care) 04/2015
1	Intranasal Administration 12/2014
1	Therapeutics 09/2014